AAV Vector-Mediated Gene Delivery to Substantia Nigra Dopamine Neurons: Implications for Gene Therapy and Disease Models

Gene delivery using adeno-associated virus (AAV) vectors is a widely used method to transduce neurons in the brain, especially due to its safety, efficacy, and long-lasting expression. In addition, by varying AAV serotype, promotor, and titer, it is possible to affect the cell specificity of express...

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Detalles Bibliográficos
Autores principales: Albert, Katrina, Voutilainen, Merja H., Domanskyi, Andrii, Airavaara, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333052/
https://www.ncbi.nlm.nih.gov/pubmed/28208742
http://dx.doi.org/10.3390/genes8020063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333052/
https://www.ncbi.nlm.nih.gov/pubmed/28208742
http://dx.doi.org/10.3390/genes8020063

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