Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks

ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the...

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Detalles Bibliográficos
Autores principales: Rakhimova, Alina, Ura, Seiji, Hsu, Duen-Wei, Wang, Hong-Yu, Pears, Catherine J., Lakin, Nicholas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333086/
https://www.ncbi.nlm.nih.gov/pubmed/28252050
http://dx.doi.org/10.1038/srep43750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333086/
https://www.ncbi.nlm.nih.gov/pubmed/28252050
http://dx.doi.org/10.1038/srep43750

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