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Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks
ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the...
Autores principales: | Rakhimova, Alina, Ura, Seiji, Hsu, Duen-Wei, Wang, Hong-Yu, Pears, Catherine J., Lakin, Nicholas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333086/ https://www.ncbi.nlm.nih.gov/pubmed/28252050 http://dx.doi.org/10.1038/srep43750 |
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