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IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting

Genetic evolution that occurs during cancer progression enables tumour heterogeneity, thereby fostering tumour adaptation, therapeutic resistance and metastatic potential. Immune responses are known to select (immunoedit) tumour cells displaying immunoevasive properties. Here we address the role of...

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Detalles Bibliográficos
Autores principales: Takeda, Kazuyoshi, Nakayama, Masafumi, Hayakawa, Yoshihiro, Kojima, Yuko, Ikeda, Hiroaki, Imai, Naoko, Ogasawara, Kouetsu, Okumura, Ko, Thomas, David M., Smyth, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333095/
https://www.ncbi.nlm.nih.gov/pubmed/28233863
http://dx.doi.org/10.1038/ncomms14607