Insights into the activity of maturation inhibitor PF-46396 on HIV-1 clade C

HIV maturation inhibitors are an emerging class of anti-retroviral compounds that inhibit the viral protease-mediated cleavage of the Gag, CA-SP1 (capsid-spacer peptide 1) peptide to mature CA. The first-in-class maturation inhibitor bevirimat (BVM) displayed potent activity against HIV-1 clade B bu...

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Detalles Bibliográficos
Autores principales: Ghimire, Dibya, Timilsina, Uddhav, Srivastava, Tryambak Pratap, Gaur, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333120/
https://www.ncbi.nlm.nih.gov/pubmed/28252110
http://dx.doi.org/10.1038/srep43711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333120/
https://www.ncbi.nlm.nih.gov/pubmed/28252110
http://dx.doi.org/10.1038/srep43711

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