A genetically encoded toolkit for tracking live-cell histidine dynamics in space and time

High-resolution spatiotemporal imaging of histidine in single living mammalian cells faces technical challenges. Here, we developed a series of ratiometric, highly responsive, and single fluorescent protein-based histidine sensors of wide dynamic range. We used these sensors to quantify subcellular...

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Detalles Bibliográficos
Autores principales: Hu, Hanyang, Gu, Yanfang, Xu, Lei, Zou, Yejun, Wang, Aoxue, Tao, Rongkun, Chen, Xianjun, Zhao, Yuzheng, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333150/
https://www.ncbi.nlm.nih.gov/pubmed/28252043
http://dx.doi.org/10.1038/srep43479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333150/
https://www.ncbi.nlm.nih.gov/pubmed/28252043
http://dx.doi.org/10.1038/srep43479

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