Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2

The atypical MAP kinases ERK3 and ERK4 are activated by phosphorylation of a serine residue lying within the activation loop signature sequence S-E-G. However, the regulation of ERK3 and ERK4 phosphorylation and activity is poorly understood. Here we report that the inducible nuclear dual-specificit...

Descripción completa

Detalles Bibliográficos
Autores principales: Perander, Maria, Al-Mahdi, Rania, Jensen, Thomas C., Nunn, Jennifer A. L., Kildalsen, Hanne, Johansen, Bjarne, Gabrielsen, Mads, Keyse, Stephen M., Seternes, Ole-Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333157/
https://www.ncbi.nlm.nih.gov/pubmed/28252035
http://dx.doi.org/10.1038/srep43471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333157/
https://www.ncbi.nlm.nih.gov/pubmed/28252035
http://dx.doi.org/10.1038/srep43471

Ejemplares similares