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A Systematic Approach to Time-series Metabolite Profiling and RNA-seq Analysis of Chinese Hamster Ovary Cell Culture

Chinese hamster ovary (CHO) cells are the primary host used for biopharmaceutical protein production. The engineering of CHO cells to produce higher amounts of biopharmaceuticals has been highly dependent on empirical approaches, but recent high-throughput “omics” methods are changing the situation...

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Detalles Bibliográficos
Autores principales: Hsu, Han-Hsiu, Araki, Michihiro, Mochizuki, Masao, Hori, Yoshimi, Murata, Masahiro, Kahar, Prihardi, Yoshida, Takanobu, Hasunuma, Tomohisa, Kondo, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333161/
https://www.ncbi.nlm.nih.gov/pubmed/28252038
http://dx.doi.org/10.1038/srep43518