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Theoretical model of mitotic spindle microtubule growth for FRAP curve interpretation

BACKGROUND: Spindle FRAP curves depend on the kinetic parameters of microtubule polymerization and depolymerization. The empirical FRAP curve proposed earlier permits determination of only one such dynamic parameter, commonly called the "tubulin turnover". The aim of our study was to build...

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Detalles Bibliográficos
Autores principales: Omelyanchuk, Leonid V., Munzarova, Alina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333183/
https://www.ncbi.nlm.nih.gov/pubmed/28466790
http://dx.doi.org/10.1186/s12918-016-0378-9