The human two-pore channel 1 is modulated by cytosolic and luminal calcium

Two-pore channels (TPC) are intracellular endo-lysosomal proteins with only recently emerging roles in organellar signalling and involvement in severe human diseases. Here, we investigated the functional properties of human TPC1 expressed in TPC-free vacuoles from Arabidopsis thaliana cells. Large (...

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Detalles Bibliográficos
Autores principales: Lagostena, Laura, Festa, Margherita, Pusch, Michael, Carpaneto, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333365/
https://www.ncbi.nlm.nih.gov/pubmed/28252105
http://dx.doi.org/10.1038/srep43900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333365/
https://www.ncbi.nlm.nih.gov/pubmed/28252105
http://dx.doi.org/10.1038/srep43900

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