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Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci

Detailed analyses of transcriptome have revealed complexity in regulation of alternative splicing (AS). These AS events often undergo modulation by genetic variants. Here we analyse RNA-sequencing data of prefrontal cortex from 206 individuals in combination with their genotypes and identify cis-act...

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Detalles Bibliográficos
Autores principales: Takata, Atsushi, Matsumoto, Naomichi, Kato, Tadafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333373/
https://www.ncbi.nlm.nih.gov/pubmed/28240266
http://dx.doi.org/10.1038/ncomms14519