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Overexpression of aquaporin 4 in articular chondrocytes exacerbates the severity of adjuvant-induced arthritis in rats: an in vivo and in vitro study

BACKGROUND: The dysfunction of articular chondrocytes is a crucial step in rheumatoid arthritis (RA) pathogenesis while its molecular mechanisms are not fully known. This study was aimed to investigate the expression of aquaporin 4 (AQP4) in articular chondrocytes of adjuvant-induced arthritis (AIA)...

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Detalles Bibliográficos
Autores principales: Cai, Li, Lei, Chao, Li, Rong, Chen, Wei-na, Hu, Cheng-mu, Chen, Xiao-yu, Li, Chun-mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333381/
https://www.ncbi.nlm.nih.gov/pubmed/28265203
http://dx.doi.org/10.1186/s12950-017-0153-8