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Combining phylogenetic footprinting with motif models incorporating intra-motif dependencies
BACKGROUND: Transcriptional gene regulation is a fundamental process in nature, and the experimental and computational investigation of DNA binding motifs and their binding sites is a prerequisite for elucidating this process. Approaches for de-novo motif discovery can be subdivided in phylogenetic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333389/ https://www.ncbi.nlm.nih.gov/pubmed/28249564 http://dx.doi.org/10.1186/s12859-017-1495-1 |