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Enhancement of scutellarin oral delivery efficacy by vitamin B12-modified amphiphilic chitosan derivatives to treat type II diabetes induced-retinopathy

BACKGROUND: Diabetic retinopathy is the most common complication in diabetic patients relates to high expression of VEGF and microaneurysms. Scutellarin (Scu) turned out to be effective against diabetes related vascular endothelial cell dysfunction. However, its clinical applications have been limit...

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Detalles Bibliográficos
Autores principales: Wang, Jingnan, Tan, Jiayun, Luo, Jiahao, Huang, Peilin, Zhou, Wuyi, Chen, Luming, Long, Lingli, Zhang, Li-ming, Zhu, Banghao, Yang, Liqun, Deng, David Y. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333415/
https://www.ncbi.nlm.nih.gov/pubmed/28249594
http://dx.doi.org/10.1186/s12951-017-0251-z