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Efficacy and safety of de-escalation therapy to ertapenem for treatment of infections caused by extended-spectrum-β-lactamase-producing Enterobacteriaceae: an open-label randomized controlled trial

BACKGROUND: Carbapenem antibiotics are considered the treatment of choice for serious extended-spectrum beta-lactamase (ESBL)-producing Gram-negative bacteria (GNB) infections. The study objectives were to evaluate efficacy and safety of de-escalation therapy to ertapenem for treatment of infections...

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Detalles Bibliográficos
Autores principales: Rattanaumpawan, Pinyo, Werarak, Peerawong, Jitmuang, Anupop, Kiratisin, Pattarachai, Thamlikitkul, Visanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333449/
https://www.ncbi.nlm.nih.gov/pubmed/28249572
http://dx.doi.org/10.1186/s12879-017-2284-1