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Camelid V(H)H affinity ligands enable separation of closely related biopharmaceuticals

Interest in new and diverse classes of molecules such as recombinant toxins, enzymes, and blood factors continues to grow for use a biotherapeutics. Compared to monoclonal antibodies, these novel drugs typically lack a commercially available affinity chromatography option, which leads to greater pro...

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Detalles Bibliográficos
Autores principales: Pabst, Timothy M., Wendeler, Michaela, Wang, Xiangyang, Bezemer, Sandra, Hermans, Pim, Hunter, Alan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333455/
https://www.ncbi.nlm.nih.gov/pubmed/27677057
http://dx.doi.org/10.1002/biot.201600357