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Proteomics insights into DNA damage response and translating this knowledge to clinical strategies
Genomic instability is a critical driver in the process of cancer formation. At the same time, inducing DNA damage by irradiation or genotoxic compounds constitutes a key therapeutic strategy to kill fast‐dividing cancer cells. Sensing of DNA lesions initiates a complex set of signalling pathways, c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333460/ https://www.ncbi.nlm.nih.gov/pubmed/27682984 http://dx.doi.org/10.1002/pmic.201600018 |