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Proteomics insights into DNA damage response and translating this knowledge to clinical strategies

Genomic instability is a critical driver in the process of cancer formation. At the same time, inducing DNA damage by irradiation or genotoxic compounds constitutes a key therapeutic strategy to kill fast‐dividing cancer cells. Sensing of DNA lesions initiates a complex set of signalling pathways, c...

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Detalles Bibliográficos
Autores principales:	von Stechow, Louise, Olsen, Jesper V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Biomedicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333460/ https://www.ncbi.nlm.nih.gov/pubmed/27682984 http://dx.doi.org/10.1002/pmic.201600018

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