Imatinib and its combination with 2,5-dimethyl-celecoxibinduces apoptosis of human HT-29 colorectal cancer cells

Mono-targeting by imatinib as a main antitumor agent does not always accomplish complete cancer suppression. 2,5-dimethyl-celecoxib (DMC) is a close structural analog of the selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib, that lacks COX-2 inhibitory function. In this study, we aimed to show...

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Detalles Bibliográficos
Autores principales: Atari-Hajipirloo, Somayeh, Nikanfar, Saba, Heydari, Amir, Kheradmand, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333482/
https://www.ncbi.nlm.nih.gov/pubmed/28255316
http://dx.doi.org/10.4103/1735-5362.199049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333482/
https://www.ncbi.nlm.nih.gov/pubmed/28255316
http://dx.doi.org/10.4103/1735-5362.199049

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