Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C

A detailed molecular understanding of botulinum neurotoxin (BoNT)/host-cell-receptor interactions is fundamental both for developing strategies against botulism and for generating improved BoNT variants for medical applications. The X-ray crystal structure of the receptor-binding domain (H(C)) of Bo...

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Detalles Bibliográficos
Autores principales: Benoit, Roger M., Schärer, Martin A., Wieser, Mara M., Li, Xiaodan, Frey, Daniel, Kammerer, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333631/
https://www.ncbi.nlm.nih.gov/pubmed/28252640
http://dx.doi.org/10.1038/srep43588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333631/
https://www.ncbi.nlm.nih.gov/pubmed/28252640
http://dx.doi.org/10.1038/srep43588

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