Aggretin Venom Polypeptide as a Novel Anti-angiogenesis Agent by Targeting Integrin alpha2beta1

VEGF and VEGFR antibodies have been used as a therapeutic strategy to inhibit angiogenesis in many diseases; however, frequent and repeated administration of these antibodies to patients induces immunogenicity. In previous studies, we demonstrated that aggretin, a heterodimeric snake venom C-type le...

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Detalles Bibliográficos
Autores principales: Chung, Ching Hu, Chang, Chien Hsin, Hsu, Chun Chieh, Lin, Kung Tin, Peng, Hui Chin, Huang, Tur Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333632/
https://www.ncbi.nlm.nih.gov/pubmed/28252668
http://dx.doi.org/10.1038/srep43612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333632/
https://www.ncbi.nlm.nih.gov/pubmed/28252668
http://dx.doi.org/10.1038/srep43612

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