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Chromatin states shape insertion profiles of the piggyBac, Tol2 and Sleeping Beauty transposons and murine leukemia virus

DNA transposons and retroviruses are versatile tools in functional genomics and gene therapy. To facilitate their application, we conducted a genome-wide insertion site profiling of the piggyBac (PB), Tol2 and Sleeping Beauty (SB) transposons and the murine leukemia virus (MLV) in mouse embryonic st...

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Detalles Bibliográficos
Autores principales: Yoshida, Junko, Akagi, Keiko, Misawa, Ryo, Kokubu, Chikara, Takeda, Junji, Horie, Kyoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333637/
https://www.ncbi.nlm.nih.gov/pubmed/28252665
http://dx.doi.org/10.1038/srep43613