Intravaginal immunisation using a novel antigen-releasing ring device elicits robust vaccine antigen-specific systemic and mucosal humoral immune responses

The generation of effective levels of antigen-specific immunity at the mucosal sites of pathogen entry is a key goal for vaccinologists. We explored topical vaginal application as an approach to initiate local antigen-specific immunity, enhance previously existing systemic immunity or re-target resp...

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Detalles Bibliográficos
Autores principales: McKay, Paul F., Mann, Jamie F.S., Pattani, Aditya, Kett, Vicky, Aldon, Yoann, King, Deborah, Malcolm, R. Karl, Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333785/
https://www.ncbi.nlm.nih.gov/pubmed/28115243
http://dx.doi.org/10.1016/j.jconrel.2017.01.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333785/
https://www.ncbi.nlm.nih.gov/pubmed/28115243
http://dx.doi.org/10.1016/j.jconrel.2017.01.018

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