Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis

Platelets modulate the process of cancer metastasis. However, current knowledge on the direct interaction of platelets and tumor cells is mostly based on findings obtained in vitro. We addressed the role of the platelet fibrinogen receptor glycoprotein IIb (integrin αIIb) for experimental melanoma m...

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Detalles Bibliográficos
Autores principales: Echtler, Katrin, Konrad, Ildiko, Lorenz, Michael, Schneider, Simon, Hofmaier, Sebastian, Plenagl, Florian, Stark, Konstantin, Czermak, Thomas, Tirniceriu, Anca, Eichhorn, Martin, Walch, Axel, Enders, Georg, Massberg, Steffen, Schulz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333841/
https://www.ncbi.nlm.nih.gov/pubmed/28253287
http://dx.doi.org/10.1371/journal.pone.0172788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333841/
https://www.ncbi.nlm.nih.gov/pubmed/28253287
http://dx.doi.org/10.1371/journal.pone.0172788

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