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Dopamine D(2) receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson’s disease drugs, levodopa and piribedil, in neuronal cells

Although levodopa is the first-line medication for the treatment of Parkinson’s disease (PD) showing unsurpassable efficiency, its chronic use causes dyskinesia. Accordingly, dopamine agonists are increasingly employed as monotherapy or in combination with levodopa to reduce the risk of motor compli...

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Detalles Bibliográficos
Autores principales: Lu, Jing, Li, Xiaohang, Wang, Qinying, Pei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333886/
https://www.ncbi.nlm.nih.gov/pubmed/28253352
http://dx.doi.org/10.1371/journal.pone.0173240