Cargando…
Dopamine D(2) receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson’s disease drugs, levodopa and piribedil, in neuronal cells
Although levodopa is the first-line medication for the treatment of Parkinson’s disease (PD) showing unsurpassable efficiency, its chronic use causes dyskinesia. Accordingly, dopamine agonists are increasingly employed as monotherapy or in combination with levodopa to reduce the risk of motor compli...
Autores principales: | Lu, Jing, Li, Xiaohang, Wang, Qinying, Pei, Gang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333886/ https://www.ncbi.nlm.nih.gov/pubmed/28253352 http://dx.doi.org/10.1371/journal.pone.0173240 |
Ejemplares similares
-
Clinical Effects of Piribedil in Adjuvant Treatment of Parkinson’s Disease: A Meta-Analysis
por: Peihua, Lu, et al.
Publicado: (2018) -
Roles of Dopamine D(2) Receptor Subregions in Interactions with β-Arrestin2
por: Zhang, Xiaohan, et al.
Publicado: (2016) -
β-Arrestin1 regulates γ-secretase complex assembly and modulates amyloid-β pathology
por: Liu, Xiaosong, et al.
Publicado: (2013) -
Levodopa/Benserazide PLGA Microsphere Prevents L-Dopa–Induced Dyskinesia via Lower β-Arrestin2 in 6-Hydroxydopamine Parkinson’s Rats
por: Wang, Wen-Wen, et al.
Publicado: (2019) -
Dopamine and Levodopa Prodrugs for the Treatment of Parkinson’s Disease
por: Haddad, Fatma, et al.
Publicado: (2017)