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Early type I Interferon response induces upregulation of human β-defensin 1 during acute HIV-1 infection

HIV-1 is able to evade innate antiviral responses during acute infection to establish a chronic systemic infection which, in the absence of antiretroviral therapy (ART), typically progresses to severe immunodeficiency. Understanding these early innate immune responses against HIV-1 and their mechani...

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Detalles Bibliográficos
Autores principales: Corleis, Björn, Lisanti, Antonella C., Körner, Christian, Schiff, Abigail E., Rosenberg, Eric S., Allen, Todd M., Altfeld, Marcus, Kwon, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333889/
https://www.ncbi.nlm.nih.gov/pubmed/28253319
http://dx.doi.org/10.1371/journal.pone.0173161