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A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species

Borrelia burgdorferi, the causative agent of Lyme disease in humans, is exposed to reactive oxygen and nitrogen species (ROS and RNS) in both the tick vector and vertebrate reservoir hosts. B. burgdorferi contains a limited repertoire of canonical oxidative stress response genes, suggesting that nov...

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Detalles Bibliográficos
Autores principales: Ramsey, Meghan E., Hyde, Jenny A., Medina-Perez, Diana N., Lin, Tao, Gao, Lihui, Lundt, Maureen E., Li, Xin, Norris, Steven J., Skare, Jon T., Hu, Linden T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333916/
https://www.ncbi.nlm.nih.gov/pubmed/28212410
http://dx.doi.org/10.1371/journal.ppat.1006225