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A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species
Borrelia burgdorferi, the causative agent of Lyme disease in humans, is exposed to reactive oxygen and nitrogen species (ROS and RNS) in both the tick vector and vertebrate reservoir hosts. B. burgdorferi contains a limited repertoire of canonical oxidative stress response genes, suggesting that nov...
Autores principales: | Ramsey, Meghan E., Hyde, Jenny A., Medina-Perez, Diana N., Lin, Tao, Gao, Lihui, Lundt, Maureen E., Li, Xin, Norris, Steven J., Skare, Jon T., Hu, Linden T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333916/ https://www.ncbi.nlm.nih.gov/pubmed/28212410 http://dx.doi.org/10.1371/journal.ppat.1006225 |
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