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SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication

Small ubiquitin-like modifier (SUMO) modification of chromatin has profound effects on transcription regulation. By using Kaposi’s sarcoma associated herpesvirus (KSHV) as a model, we recently demonstrated that epigenetic modification of viral chromatin by SUMO-2/3 is involved in regulating gene exp...

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Detalles Bibliográficos
Autores principales: Yang, Wan-Shan, Campbell, Mel, Chang, Pei-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333917/
https://www.ncbi.nlm.nih.gov/pubmed/28212444
http://dx.doi.org/10.1371/journal.ppat.1006216