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Quantitative and Pathologist-Read comparison of the Heterogeneity of Programmed Death-Ligand 1(PD-L1) expression in Non-Small Cell Lung Cancer

PD-L1 is expressed in a percentage of lung cancer patients and those patients show increased likelihood of response to PD-1 axis therapies. However, the methods and assays for assessment of PD-L1 using immunohistochemistry are variable and PD-L1 expression appears to be highly heterogeneous. Here, w...

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Detalles Bibliográficos
Autores principales: Rehman, Jamaal A., Han, Gang, Carvajal-Hausdorf, Daniel E., Wasserman, Brad E., Pelekanou, Vasiliki, Mani, Nikita L., McLaughlin, Joseph, Schalper, Kurt A., Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334264/
https://www.ncbi.nlm.nih.gov/pubmed/27834350
http://dx.doi.org/10.1038/modpathol.2016.186