Methylation of FOXP3 TSDR Underlies the Impaired Suppressive Function of Tregs from Long-term Belatacept-Treated Kidney Transplant Patients

Regulatory T cells (Tregs) are considered key players in the prevention of allograft rejection in transplanted patients. Belatacept (BLT) is an effective alternative to calcineurin inhibitors that appears to preserve graft survival and function; however, the impact of this drug in the homeostasis of...

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Detalles Bibliográficos
Autores principales: Alvarez Salazar, Evelyn Katy, Cortés-Hernández, Arimelek, Alemán-Muench, Germán Rodrigo, Alberú, Josefina, Rodríguez-Aguilera, Jesús R., Recillas-Targa, Félix, Chagoya de Sánchez, Victoria, Cuevas, Eric, Mancilla-Urrea, Eduardo, Pérez García, María, Mondragón-Ramírez, Guillermo, Vilatobá, Mario, Bostock, Ian, Hernández-Méndez, Erick, De Rungs, David, García-Zepeda, Eduardo A., Soldevila, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334349/
https://www.ncbi.nlm.nih.gov/pubmed/28316600
http://dx.doi.org/10.3389/fimmu.2017.00219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334349/
https://www.ncbi.nlm.nih.gov/pubmed/28316600
http://dx.doi.org/10.3389/fimmu.2017.00219

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