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Dose-Dependent Induction of an Idiotypic Cascade by Anti-Glycosaminoglycan Monoclonal Antibody in apoE(−/−) Mice: Association with Atheroprotection

Atherosclerosis, the underlying pathology of most cardiovascular diseases, is triggered by the retention of apolipoprotein B (apoB)-containing lipoproteins in the arterial wall through electrostatic interactions with glycosaminoglycan (GAG) side chains of proteoglycans. Previously, we reported the a...

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Detalles Bibliográficos
Autores principales: Sarduy, Roger, Brito, Victor, Castillo, Adriana, Soto, Yosdel, Griñán, Tania, Marleau, Sylvie, Vázquez, Ana María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334371/
https://www.ncbi.nlm.nih.gov/pubmed/28316603
http://dx.doi.org/10.3389/fimmu.2017.00232