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Progesterone Provides the Pleiotropic Neuroprotective Effect on Traumatic Brain Injury Through the Nrf2/ARE Signaling Pathway

OBJECTIVE: This study was to investigate the role of Nrf2/ARE signaling pathway in the pleiotropic neuroprotective effect of progesterone (PROG) on traumatic brain injury (TBI). METHODS: The Nrf2-knockout (Nrf2−/−) and C57 mice were respectively subjected to a lateral cortical impact injury caused b...

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Detalles Bibliográficos
Autores principales: Zhang, Mei, Wu, Jianyue, Ding, Haojun, Wu, Wentian, Xiao, Guomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334408/
https://www.ncbi.nlm.nih.gov/pubmed/27995513
http://dx.doi.org/10.1007/s12028-016-0342-y