The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling

The dry (nonneovascular) form of age‐related macular degeneration (AMD), a leading cause of blindness in the elderly, has few, if any, treatment options at present. It is characterized by early accumulation of cellular waste products in the retinal pigmented epithelium (RPE); rejuvenating impaired l...

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Detalles Bibliográficos
Autores principales: Shang, Peng, Valapala, Mallika, Grebe, Rhonda, Hose, Stacey, Ghosh, Sayan, Bhutto, Imran A., Handa, James T., Lutty, Gerard A., Lu, Lixia, Wan, Jun, Qian, Jiang, Sergeev, Yuri, Puertollano, Rosa, Zigler, J. Samuel, Xu, Guo‐Tong, Sinha, Debasish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334531/
https://www.ncbi.nlm.nih.gov/pubmed/28083894
http://dx.doi.org/10.1111/acel.12561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334531/
https://www.ncbi.nlm.nih.gov/pubmed/28083894
http://dx.doi.org/10.1111/acel.12561

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