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The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling
The dry (nonneovascular) form of age‐related macular degeneration (AMD), a leading cause of blindness in the elderly, has few, if any, treatment options at present. It is characterized by early accumulation of cellular waste products in the retinal pigmented epithelium (RPE); rejuvenating impaired l...
Autores principales: | Shang, Peng, Valapala, Mallika, Grebe, Rhonda, Hose, Stacey, Ghosh, Sayan, Bhutto, Imran A., Handa, James T., Lutty, Gerard A., Lu, Lixia, Wan, Jun, Qian, Jiang, Sergeev, Yuri, Puertollano, Rosa, Zigler, J. Samuel, Xu, Guo‐Tong, Sinha, Debasish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334531/ https://www.ncbi.nlm.nih.gov/pubmed/28083894 http://dx.doi.org/10.1111/acel.12561 |
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