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Homocysteine modulates 5‐lipoxygenase expression level via DNA methylation
Elevated levels of homocysteinemia (Hcy), a risk factor for late‐onset Alzheimer's disease (AD), have been associated with changes in cell methylation. Alzheimer's disease is characterized by an upregulation of the 5‐lipoxygenase (5LO), whose promoter is regulated by methylation. However,...
Autores principales: | Li, Jian‐Guo, Barrero, Carlos, Gupta, Sapna, Kruger, Warren D., Merali, Salim, Praticò, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334532/ https://www.ncbi.nlm.nih.gov/pubmed/27896923 http://dx.doi.org/10.1111/acel.12550 |
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