Aging impairs double‐strand break repair by homologous recombination in Drosophila germ cells

Aging is characterized by genome instability, which contributes to cancer formation and cell lethality leading to organismal decline. The high levels of DNA double‐strand breaks (DSBs) observed in old cells and premature aging syndromes are likely a primary source of genome instability, but the unde...

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Detalles Bibliográficos
Autores principales: Delabaere, Laetitia, Ertl, Henry A., Massey, Dashiell J., Hofley, Carolyn M., Sohail, Faraz, Bienenstock, Elisa J., Sebastian, Hans, Chiolo, Irene, LaRocque, Jeannine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334535/
https://www.ncbi.nlm.nih.gov/pubmed/28000382
http://dx.doi.org/10.1111/acel.12556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334535/
https://www.ncbi.nlm.nih.gov/pubmed/28000382
http://dx.doi.org/10.1111/acel.12556

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