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T Cell Receptor and Cytokine Signaling Can Function at Different Stages to Establish and Maintain Transcriptional Memory and Enable T Helper Cell Differentiation

Experienced T cells exhibit immunological memory via a rapid recall response, responding to restimulation much faster than naïve T cells. The formation of immunological memory starts during an initial slow response, when naïve T cells become transformed to proliferating T blast cells, and inducible...

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Detalles Bibliográficos
Autores principales: Bevington, Sarah L., Cauchy, Pierre, Withers, David R., Lane, Peter J. L., Cockerill, Peter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334638/
https://www.ncbi.nlm.nih.gov/pubmed/28316598
http://dx.doi.org/10.3389/fimmu.2017.00204