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Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity

Telomerase activation and telomere maintenance are critical for cellular immortalization and transformation. PIN2/TERF1-interacting telomerase inhibitor 1 (PinX1) is a telomerase regulator and the aberrant expression of PinX1 causes telomere shortening. Identifying PinX1-interacting proteins is impo...

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Detalles Bibliográficos
Autores principales: Cheung, Derek Hang-Cheong, Ho, Sai-Tim, Lau, Kwok-Fai, Jin, Rui, Wang, Ya-Nan, Kung, Hsiang-Fu, Huang, Jun-Jian, Shaw, Pang-Chui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334639/
https://www.ncbi.nlm.nih.gov/pubmed/28255170
http://dx.doi.org/10.1038/srep43650