Cholesterol impairment contributes to neuroserpin aggregation

Intraneural accumulation of misfolded proteins is a common feature of several neurodegenerative pathologies including Alzheimer’s and Parkinson’s diseases, and Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB). FENIB is a rare disease due to a point mutation in neuroserpin which acce...

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Detalles Bibliográficos
Autores principales: Giampietro, Costanza, Lionetti, Maria Chiara, Costantini, Giulio, Mutti, Federico, Zapperi, Stefano, La Porta, Caterina A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334643/
https://www.ncbi.nlm.nih.gov/pubmed/28255164
http://dx.doi.org/10.1038/srep43669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334643/
https://www.ncbi.nlm.nih.gov/pubmed/28255164
http://dx.doi.org/10.1038/srep43669

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