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Multiscale image analysis reveals structural heterogeneity of the cell microenvironment in homotypic spheroids
Three-dimensional multicellular aggregates such as spheroids provide reliable in vitro substitutes for tissues. Quantitative characterization of spheroids at the cellular level is fundamental. We present the first pipeline that provides three-dimensional, high-quality images of intact spheroids at c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334646/ https://www.ncbi.nlm.nih.gov/pubmed/28255161 http://dx.doi.org/10.1038/srep43693 |