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Mapping sites of herpes simplex virus type 1 glycoprotein D that permit insertions and impact gD and gB receptors usage

Glycoprotein D (gD) of herpes simplex virus type 1 (HSV-1) is one of four glycoproteins essential for HSV entry and cell fusion. The purpose of this study was to determine the plasticity of gD to tolerate insertion or deletion mutations and to construct an oncolytic HSV-1 that utilizes the disialoga...

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Detalles Bibliográficos
Autores principales: Fan, Qing, Kopp, Sarah, Connolly, Sarah A., Muller, William J., Longnecker, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334651/
https://www.ncbi.nlm.nih.gov/pubmed/28255168
http://dx.doi.org/10.1038/srep43712