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PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology

The G-protein coupled, protease-activated receptor 1 (PAR1) is a membrane protein expressed in astrocytes. Fine astrocytic processes are in tight contact with neurons and blood vessels and shape excitatory synaptic transmission due to their abundant expression of glutamate transporters. PAR1 is prot...

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Detalles Bibliográficos
Autores principales: Sweeney, Amanda M., Fleming, Kelsey E., McCauley, John P., Rodriguez, Marvin F., Martin, Elliot T., Sousa, Alioscka A., Leapman, Richard D., Scimemi, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335386/
https://www.ncbi.nlm.nih.gov/pubmed/28256580
http://dx.doi.org/10.1038/srep43606