Cargando…
PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology
The G-protein coupled, protease-activated receptor 1 (PAR1) is a membrane protein expressed in astrocytes. Fine astrocytic processes are in tight contact with neurons and blood vessels and shape excitatory synaptic transmission due to their abundant expression of glutamate transporters. PAR1 is prot...
Autores principales: | Sweeney, Amanda M., Fleming, Kelsey E., McCauley, John P., Rodriguez, Marvin F., Martin, Elliot T., Sousa, Alioscka A., Leapman, Richard D., Scimemi, Annalisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335386/ https://www.ncbi.nlm.nih.gov/pubmed/28256580 http://dx.doi.org/10.1038/srep43606 |
Ejemplares similares
-
Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1
por: McCauley, John P., et al.
Publicado: (2020) -
Regulation of Glutamate, GABA and Dopamine Transporter Uptake, Surface Mobility and Expression
por: Ryan, Renae M., et al.
Publicado: (2021) -
Astrocytes and the Warning Signs of Intracerebral Hemorrhagic Stroke
por: Scimemi, Annalisa
Publicado: (2018) -
NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes
por: Mahmoud, Shaimaa, et al.
Publicado: (2019) -
Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release
por: Mahmoud, Shaimaa, et al.
Publicado: (2019)