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EZH2 protein expression in normal breast epithelium and risk of breast cancer: results from the Nurses’ Health Studies

BACKGROUND: Enhancer of zeste homolog 2 (EZH2) is a polycomb-group protein that is involved in stem cell renewal and carcinogenesis. In breast cancer, increased EZH2 expression is associated with aggressiveness and has been suggested to identify normal breast epithelium at increased risk of breast c...

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Detalles Bibliográficos
Autores principales: Beca, Francisco, Kensler, Kevin, Glass, Benjamin, Schnitt, Stuart J., Tamimi, Rulla M., Beck, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335498/
https://www.ncbi.nlm.nih.gov/pubmed/28253895
http://dx.doi.org/10.1186/s13058-017-0817-6