A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects by suppressing IL-1β-induced activation of AP-1 in human OA chondrocytes

Osteoarthritis (OA) is a common joint disorder with varying degrees of inflammation and sustained oxidative stress. The root extract of Scutellaria baicalensis (SBE) has been used for the treatment of inflammatory and other diseases. Here, we performed activity-guided HPLC-fractionation of SBE, iden...

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Detalles Bibliográficos
Autores principales: Khan, Nazir M., Haseeb, Abdul, Ansari, Mohammad Y., Haqqi, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335554/
https://www.ncbi.nlm.nih.gov/pubmed/28256567
http://dx.doi.org/10.1038/srep43789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335554/
https://www.ncbi.nlm.nih.gov/pubmed/28256567
http://dx.doi.org/10.1038/srep43789

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