Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein

Astroglial pathology is seen in various neurodegenerative diseases including frontotemporal dementia (FTD), which can be caused by mutations in the gene encoding the microtubule-associated protein TAU (MAPT). Here, we applied a stem cell model of FTD to examine if FTD astrocytes carry an intrinsic p...

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Detalles Bibliográficos
Autores principales: Hallmann, Anna-Lena, Araúzo-Bravo, Marcos J., Mavrommatis, Lampros, Ehrlich, Marc, Röpke, Albrecht, Brockhaus, Johannes, Missler, Markus, Sterneckert, Jared, Schöler, Hans R., Kuhlmann, Tanja, Zaehres, Holm, Hargus, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335603/
https://www.ncbi.nlm.nih.gov/pubmed/28256506
http://dx.doi.org/10.1038/srep42991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335603/
https://www.ncbi.nlm.nih.gov/pubmed/28256506
http://dx.doi.org/10.1038/srep42991

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