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Association of Topoisomerase II (TOP2A) and Dual-Specificity Phosphatase 6 (DUSP6) Single Nucleotide Polymorphisms with Radiation Treatment Response and Prognosis of Lung Cancer in Han Chinese

BACKGROUND: Mutations of DNA topoisomerase II (TOP2A) are associated with chemotherapy resistance, whereas dual-specificity phosphatase 6 (DUSP6) negatively regulates members of the mitogen-activated protein (MAP) kinase superfamily to control cell proliferation. This study assessed TOP2A and DUSP6...

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Detalles Bibliográficos
Autores principales: Wang, Tian-Lu, Ren, Yang-Wu, Wang, He-Tong, Yu, Hong, Zhao, Yu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335646/
https://www.ncbi.nlm.nih.gov/pubmed/28231233
http://dx.doi.org/10.12659/MSM.899060