Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma

In this study, we first performed whole exome sequencing of DNA from 10 untreated and clinically annotated fresh frozen nasopharyngeal carcinoma (NPC) biopsies and matched bloods to identify somatically mutated genes that may be amenable to targeted therapeutic strategies. We identified a total of 3...

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Detalles Bibliográficos
Autores principales: Chow, Yock Ping, Tan, Lu Ping, Chai, San Jiun, Abdul Aziz, Norazlin, Choo, Siew Woh, Lim, Paul Vey Hong, Pathmanathan, Rajadurai, Mohd Kornain, Noor Kaslina, Lum, Chee Lun, Pua, Kin Choo, Yap, Yoke Yeow, Tan, Tee Yong, Teo, Soo Hwang, Khoo, Alan Soo-Beng, Patel, Vyomesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335658/
https://www.ncbi.nlm.nih.gov/pubmed/28256603
http://dx.doi.org/10.1038/srep42980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335658/
https://www.ncbi.nlm.nih.gov/pubmed/28256603
http://dx.doi.org/10.1038/srep42980

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